Alginate and Ã?²-cyclodextrin were used to produce easily dosable and spray-dried microsystems of a dried blood orange extract with\nantidysmetabolic properties, obtained from a by-product fluid extract. The spray-dried applied conditions were able to obtain a\nconcentrate dried extract without the loss of AOA and with TPC and TMA values of 35ââ?¬â??40% higher than that of the starting\nmaterial. They were also effective in producing microparticles with 80ââ?¬â??100% of encapsulation efficiency. The 2% sodium\nalginate was capable of improving the extract shelf life, while the beta-cyclodextrin (1 : 1 molar ratio with dried extract)\nprolonged the extract antioxidant efficiency by 6 hours. The good inhibition effect of the dried extract on the AGE formation\nand the MMP-2 and MMP-9 activity is presumably due to a synergic effect exerted by both anthocyanin and bioflavonoid\nextract compounds and was improved by the use of alginate and cyclodextrin.
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